6 Most Important Cannabinoids And Their Purposes

What are cannabinoids? What is their purpose and can they really cure cancer and many life-threatening diseases? The cannabis plant has been used for tens of thousands of years. Even the early civilizations recognized its healing properties and used it in producing ropes and twine. The chemical structure of the cannabis varies through its life cycle and contains over 500 compounds, but only 100 are known as cannabinoids.

These compounds affect the cannabinoid receptors present in the human body. They have a direct impact on neurotransmitter release in the brain, which influence the way we process data, and interact with other chemical compounds.

The receptors CB1 and CB2, are placed in different areas of our brain and the nervous system. In this case, they can control various functions and alter different aspects of our health.

Currently, the two most popular cannabinoids are TCH, famous for its psychoactive properties and CBD because of its allegedly medical benefits. So, let’s discover what influence they have on our lives and what can cannabinoids cure.

List Of The Most Important Cannabinoids

image of cannabinoid

Cannabigerol (CBG)

CBG, or short for cannabigerol is a cannabinoid found in an early growth cycle, which makes it challenging to collect in large quantities. However, this substance is not psychoactive, and it can be cultivated via hemp.  Due to its medical potential, CBG has become a prime target for many scientific studies.

Antibiotic – it was one of the treatments used on the MRSA virus in 2008. Considering the antibiotic properties, it is stronger than CBN and similar to CBD. The CGB is also excellent for your skin; it doesn’t only prevent the redness but also shows the excellent results with Psoriasis.

Antitumor – in 1998 the Korean researcher discovered that CBG was efficient in slowing down the growth of cancerous cells in the mouth. The more recent studies found that this compound has modest anti-tumor effects in prostate cancer cells.

Mood stabilizer – it increases serotonin levels in your brain, making you happier.

Cannabichromene (CBC)

CBC is the third most crucial cannabinoid in the cannabis plant and, in some cases, may take the lead over CBD. The CBC is non-intoxicating, and it has a couple of benefits that scientists find interesting.

Anti-inflammatory – this compound is efficient at fighting inflammation on its own. 2010 research discovered it’s even more effective when combined with THC. While scientists have been successful in isolating more than 100 different cannabinoids, they found that components work best when in harmony.

Antidepressant

So far, many scientific studies have been conducted on mice, and there is a sure way to test whether a rodent is depressed. You should suspend its tail and see how much it struggles to get away. The more the mouse struggles, the better its mood is. The mice that were injected with CBC fought significantly more than the mice which were treated with other cannabinoids.

Cannabidiols (CBD)

Short for cannabidiol, CBD is the second most popular cannabinoid. Same as THC, the list of its medical properties keeps getting longer. CBD is not psychoactive, and it’s now legal in the majority of states.

This chemical has found its purpose in many health disorders.

Epilepsy – in 2012, one of the most important studies was published, when doctors discovered that CBD affects the temporal lobe with animals and stops seizures. This evidence helped scientists strongly support CBD as a potent remedy for a wide range of human epilepsies.

Alzheimer’s, Multiple Sclerosis, and Parkinson’s – the doctors are still trying to discover the processes behind the neurodegenerative diseases like Alzheimer’s. So far, we know it’s connected with the protein called pathway.

But, recently shocking discovery has been made, in fact, CBD can actually guard the nerve cells against degenerative diseases, which is a highly promising aspect of cannabidiol.

Painkiller – you have probably heard many stories about medical cannabis, and it is rapidly becoming alternative to dangerous and addictive pain relievers. In 2015, one study compared CBD to morphine. It turned out that CBD worked well in combination with morphine and didn’t show any side effects.

In this case, patients can use this compound to treat acute pain conditions.

Cancer – the disease of the 21st century, but unfortunately, no one has been able to find the cure. The doctors are focusing their full attention on cancer treatments, and one of them might be our salvation. They discovered that CBD slows down the progression of many types of cancer, such as breast, lung, prostate, and colon.

Tetrahydrocannabinol (THC)

THC is a chemical responsible for most of marijuana’s physiological effects. It stimulates cells in the brain to release dopamine, which creates euphoria and make us happy. THC also intervenes with how we process data in the hypothalamus.

This part of the brain is responsible for creating new memories. In this case, THC can cause hallucinations, change our perception and induce delusions. On average, the effects last for two hours and kick in 10 to 30 minutes after injection.

With some patients, psychomotor impairment may continue even after the “high” effect has stopped. So, this treatment should be done under controlled conditions, only with a doctor’s supervision.

Considering the side-effects, the THC often includes happiness, anxiety, tachycardia, short-term memory loss, sedation, sedation, relaxation and pain relief. The recent studies discovered that consummation of THC could trigger the relapse in schizophrenic symptoms.

However, there are a lot of people approving the medical use of marijuana. As of 2017, the half of U.S. has legalized or decimalized the use of cannabis. In most case, THC is extracted from the marijuana plant or synthesized.

The FDA approved drug dronabinol, which is used to treat or prevent nausea with cancer-related cases. You have probably heard of cannabis oil, the main compound in this oil is TCH, and it has the power to destroy the cancer cell. But, the oil needs to contain more than 85% of THC to be useful.

Also, many patients with AIDS use THC to increase appetite, and it has a similar structure to resinous oil.

image of Tetrahydrocannabinol

Cannabinol (CBN) and cannabinodiol (CBDL)

CBN is extracted from a dry flower when it has gone a bit stale. If you leave a plant sitting on the sun for some time, then you will get a product with large amounts of CBN. This chemical offers a lot of medical benefits, such as appetite stimulant, antibiotic, pain reliever, anti-asthmatic, sedative and potential medicine for glaucoma.

Among all of them, the CBN’s most notable feature is its sedative effect and according to many scientific studies, 5 mg of CBN is effective as 10mg of diazepam.

The compound CBDL is present in cannabis plant in low quantities. It is a derivate of CBD, and it can be a product of photochemical conversion of CBN. When mixed with THC this compound becomes psychotic. It is used for many health conditions and as a pain reliever, especially in patients who have cancer.

How Do Cannabinoids Work?

When it comes to cannabinoid definition and their chemical background, it isn’t very hard to determine their purpose. They are composite medical compounds that are extracted from the cannabis plant, mainly from its flowers. Our body produces the same chemicals called endocannabinoids. So, when people consume cannabis, the compounds found in the plant attach to receptors located in our brain and body, CB1 and CB2.

Cannabis has the power to change the regulation of homeostasis, which is a process that keeps various systems in our body in balance. Researchers not only discovered that our body possesses cannabinoids, but it has an entire endocannabinoid system that contains cannabinoids. This way, humans can benefit from compounds found in nature and cannabis plant.

Up to 100 different types of cannabinoids have been isolated so far, but THC has been described as a primary chemical in cannabis due to its psychoactive effects. This is one of the reasons why scientists keep researching this plant and finding possible cures for many diseases.

FAQ

What cannabinoids do humans produce?

We already mentioned endocannabinoids and how essential they might be for our body. It seems they have a crucial role in regulating inflammation processes. They are the reason why cannabinoids attach to receptors in our brain and have such a powerful effect.

When inflammation happens, the endocannabinoids act like someone is stepping on the break. They prevent the body from over performing and immune system from getting out of control. In this case, we get a balanced reaction.

What cannabinoids can get you high?

Marijuana is no longer about THC, even though it’s the most famous cannabinoid so far. We all heard about its medical properties, but it also has potent psychoactive effects, which means it will get you high in a matter of minutes.

Another compound CBN has mild psychoactive effects, you might experience a little high, but it all comes down to heavy sleepiness.

Last but not least, THCV is, even stronger than THC, it will give you a happy and euphoric high, often described as psychedelic.

When were cannabinoids discovered?

The first cannabinoids in marijuana were discovered nearly 80 years ago. While public gives credit Raphael Mechoulam for the discovery of cannabinoids, a few of them know that Roger Adams was the first who isolated compounds from the Cannabis sativa L. plant.

Adams was Harvard alumni and prominent chemist at the University of Illinois, where he spent a couple of years researching the chemistry of marijuana. CBD was the first isolated chemical substance from the rest of the plant.

How many cannabinoids are in cannabis?

According to recent studies, scientists managed to isolate more than 100 cannabinoids, and each of them shows specific effects on the human body. Of those 100, THC, CBD and CBN have substantial research behind them. The legalization process has enabled scientists to conduct more in-depth investigations of other cannabinoids.

In the future, we can expect more significant progress in this field because cannabinoids certainly captured the attention of the public. The laws are changing, and the state officials are learning to accept these changes, with the public’s best interest.

Conclusion

The area of cannabis research is vast and diverse. From biochemical studies to psychological and chemical analysis, we can say this plant has changed our perception of medicine.

However, we are still fighting for the most significant and most important research in a modern era. How to access cannabis and use it for medical purpose?

Even though many countries have taken a step back, somehow we can’t find a solution which is costing millions of people of their health.

Many doctors, scientists, and university professors have established the healing properties of the cannabis plant, but state officials are still skeptical regarding this medical field. In the future, it is possible to expect more breakthroughs, but for now, their research is limited due to laws.

You have seen the features cannabinoids have, so based on your instinct decide whether you want to give them a chance or not. You have nothing to lose, except for your health!

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